2024 Lexus Rx 350 Hybrid Mpg. Use our handy tool to get estimated annual fuel costs based on your driving habits. Overall fuel economy of 26 mpg is an improvement over the 21 mpg in our tested rx 350.
We prefer hybrid versions of the rx for smooth power delivery and quick acceleration. The epa’s data shows that the most efficient rx model is the rx350h, which carries claimed ratings of 37 mpg city and 34 mpg highway.